Developing a Telehealth + MHealth Cannabis Use Intervention for Young Adults (CAN-DO)

Boston Children's Hospital

Status: Invitation-only

Conditions: Cannabis Use Disorder

Treatments: Behavioral: Enhanced Usual Care; Behavioral: Motivational Enhancement Therapy plus Ecological Momentary Intervention

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT06661031

1R34DA060500-01A1 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The goal of this clinical trial is to determine 1) feasibility of the MOMENT-V intervention for cannabis use disorder in young adults, 2) feasibility of conducting the trial remotely, and 3) whether the MOMENT-V intervention reduces cannabis use frequency and problems. Researchers will compare the MOMENT-V intervention to usual care enhanced by a counselor meeting.

Participants will either meet with a counselor two times and use an app on their phone for two weeks, or meet with a counselor briefly one time. All participants will be asked to complete electronic surveys, interviews with a research assistant, and saliva drug testing at home over three months.

Enrollment: 65 estimated patients

Sex: All

Ages: 18 to 26 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

For the oral fluid testing pilot

Inclusion Criteria:

• Primary care patient of the Boston Children's Hospital Adolescent/Young Adult Medicine Practice
• Participation in MOMENT-V open pilot
• Ownership of a smartphone
• Availability for the 2-week study duration

Exclusion Criteria:

• Inability/Unwillingness to provide contact information
• Current pregnancy or parenting

For the pilot RCT

Inclusion Criteria:

• Primary care patient of the Boston Children's Hospital Adolescent/Young Adult Medicine Practice or Martha Eliot Health Center Adolescent Clinic
• 18 to 26 years old
• Cannabis Use Disorders Identification Test-Revised (CUDIT-R) score of ≥12
• Recreational cannabis use on >3 days/week, on average, in the past 30 days
• Ownership of a smartphone that is PIN- or password-protected
• Ability to read and speak English
• Availability for the 6-month study duration

Exclusion Criteria:

• Inability/Unwillingness to provide contact information
• Written certification from a physician for marijuana for medical use
• Current participation in a substance use treatment program or research study
• Current pregnancy or parenting
• Participation in prior MOMENT or MOMENT-V research

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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65 participants in 3 patient groups

Enhanced Usual Care arm

Other group

Description:

Participants meet with a study counselor 1-on-1 via videoconference to review a brochure containing cannabis information and treatment resources.

Treatment:

Behavioral: Enhanced Usual Care

Intervention arm

Experimental group

Description:

Participants meet with a counselor 1-on-1 via videoconference and receive MOMENT-V (mHealth intervention involving 2 Motivational Enhancement Therapy \[MET\] sessions with a trained counselor and 2 weeks of smartphone-based Ecological Momentary Assessment \[EMI\]).

Treatment:

Behavioral: Motivational Enhancement Therapy plus Ecological Momentary Intervention

Oral fluid test pilot

No Intervention group

Description:

Prior to RCT, single-arm pilot to test feasibility and acceptability of remote oral fluid testing.