Developing an Intervention to Address Suicide Risk During Substance Use Disorder

University of Michigan

Status: Completed

Conditions: Substance-Related Disorders; Suicide

Treatments: Behavioral: CBT for suicide in Substance abuse; Behavioral: Psychoeducation for substance abuse

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT01127932

5R21DA026925-02

Details and patient eligibility

About

This is a 2-year study designed to: (1) adapt and refine an existing cognitive-behavioral treatment (CBT) intervention to decrease suicidal thoughts and behaviors for use in Substance Use Disorder (SUD) treatment settings, and (2) conduct a pilot randomized controlled trial with 50 patients in treatment for SUDs comparing the CBT intervention to an enhanced control condition. Through this pilot randomized controlled trial, the investigators hope to not only obtain information about the feasibility of implementing these procedures in residential SUD treatment, but to also determine whether this intervention decreases the level of suicidal ideation, suicide attempts, hopelessness, and frequency of substance use relative to the control condition.

Full description

Existing research indicates that problematic alcohol and drug use are closely linked to both fatal and non-fatal suicide attempts. Given the strong association between substance use and suicide, an episode of substance use disorder (SUD) treatment provides a unique opportunity to decrease the likelihood of suicidal behaviors. However, there are no data on the effectiveness of specific interventions designed to decrease suicidal thoughts and behaviors during an episode of SUD treatment in individuals at high risk for suicide. Patients for this trial will be screened at the SUD treatment site for a combination of a past suicide attempt and current suicidal ideation and will be randomized to CBT or control conditions. All participants in the pilot randomized controlled trial will be assessed at baseline, at the end of treatment, and at a 3-month follow-up. From a public health perspective, SUD treatment programs contain large numbers of patients at high risk for future suicidal behaviors and therefore have the potential to play a central role in our nation's efforts to decrease suicide.

Enrollment: 56 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Must be over 18 years of age
• Report a past lifetime suicide attempt
• Report current suicidal ideation
• Resided in treatment for less than 4 weeks
• In treatment for less than 6 months

Exclusion criteria

• Mental incompetence (e.g. unable to provide informed consent)
• Diagnosis of schizophrenia or currently psychotic

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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56 participants in 2 patient groups

CBT for suicide

Experimental group

Treatment:

Behavioral: CBT for suicide in Substance abuse

Enhanced care control group

Active Comparator group

Description:

This group is designed to be an active control which provides detailed information about substance use, suicide risk, and depression without providing any CBT or other specific therapy.

Treatment:

Behavioral: Psychoeducation for substance abuse