Developing an Intervention to Prevent Visceral Adipose Tissue Accumulation

Rush

Status

Completed

Conditions

Overweight

Abdominal Obesity

Menopause

Obesity

Visceral Adipose Tissue Accumulation

Treatments

Behavioral: Multi-level intervention

Study type

Interventional

Funder types

Other

NIH

Identifiers

NCT01778712

5U01HL097894-03 (U.S. NIH Grant/Contract)

09090108

Details and patient eligibility

About

The aim of this study is to develop an intervention that will produce a sustained improvement in physical activity and chronic stress as a means to slow the menopause-related accumulation of visceral adipose tissue in mid-life women.

Enrollment

71 patients

Sex

Female

Ages

42+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Resident of the Beverly or Morgan Park neighborhood of Chicago or contiguous neighborhoods
Female
African American or Caucasian
Age 42 years or older
Intact uterus, at least one functioning ovary, at least one menstrual period in the last 12 months prior to screening.
Sufficient motivation level to make lifestyle changes, as determined by WISHFIT staff.

Exclusion criteria

Hysterectomy
Physical activity > 90 min per week
Metabolic conditions or use of medications that affect weight of visceral adipose tissue (diabetes, acquired immune deficiency syndrome, weight > 300 lbs)
Presence or history of major psychiatric comorbidity (i.e. dementia, schizophrenia, bipolar disorder, alcohol/drug addiction) in the last 6 months
History of inpatient mental health treatment
Currently prescribed antipsychotic medication
History of hallucinations or bizarre thoughts
Current pregnancy
Has been told by a physician that it is unsafe to engage in physical activity
An illness expected to limit functional status or life expectancy, including: heart failure, recent heart attack, liver cirrhosis, kidney failure, oncologic conditions, history or heart surgery, angioplasty or artery stenting.