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Developing Criteria for Cortical Resections

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The University of Chicago

Status

Completed

Conditions

Epilepsy
Tumor

Treatments

Procedure: Tissue sample (procedure/screening)

Study type

Observational

Funder types

Other

Identifiers

Details and patient eligibility

About

The purpose of this study is to study how disease processes like tumors or epilepsy spread in the brain.

Full description

The purpose of this study is to study how disease processes like tumors or epilepsy spread in the brain. During surgery small pieces of abnormal (unusual) brain tissue may be removed. We analyze these specimens using more advanced microscopic and electrophysiologic techniques than are usually applied to such tissue specimens. In addition, some tissues can be maintained in laboratory conditions to allow analysis over the longer term. No extra brain tissue is taken to perform these studies. The tissue analysis is performed by the research team and are compared to the routine (normal) electrical recordings that are taken during this type of brain surgery. Currently there are no instructions telling a doctor how much brain tissue should be cut out to prevent the spread of tumors or epilepsy. We are hoping that the results of this study help us to better know how much brain tissue needs to be removed to prevent the spread of tumors or epilepsy.

Enrollment

87 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

  • Surgical candidates with epilepsy or brain tumor(s)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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