Developing E-liquid Product Standards (Sweet Spot Study)

The Ohio State University

Status: Completed

Conditions: Nicotine; E-cigarette Use; Nicotine Vaping

Treatments: Behavioral: Vaping study EC J; Behavioral: Vaping study EC C; Behavioral: Vaping study EC G; Behavioral: Vaping study EC B; Behavioral: Vaping study EC A; Behavioral: Vaping study EC D; Behavioral: Vaping study EC E; Behavioral: Vaping study EC H; Behavioral: Vaping study EC I; Behavioral: Vaping study EC F

Study type: Interventional

Funder types: Other

Identifiers

NCT05864586

NCI-2023-03206 (Registry Identifier)

OSU-22253

Details and patient eligibility

About

The Sweet Spot Study aims to evaluate the effect of e-liquids with nicotine varying in freebase (FB) levels and concentrations on the appeal of electronic cigarettes (ECs) in young adult EC users with minimal/no history of smoking and older adult smokers.

Enrollment: 150 patients

Sex: All

Ages: 21 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Young adult e-cigarette user or older adult smoker
2. Willing to abstain from all nicotine product use for 12 hours prior to the study visit
3. Read and speak English

Exclusion criteria

1. Currently attempting to quit nicotine products
2. Currently pregnant, planning to become pregnant, or breastfeeding
3. Current or past use of tobacco products other than e-cigarettes or cigarettes
4. Self-reported diagnosis of lung disease
5. Self-reported new or unstable cardiovascular disease

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: Double Blind

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150 participants in 2 patient groups

Young adult EC users

Active Comparator group

Description:

Young Adult EC users

Treatment:

Behavioral: Vaping study EC F

Behavioral: Vaping study EC I

Behavioral: Vaping study EC H

Behavioral: Vaping study EC E

Behavioral: Vaping study EC D

Behavioral: Vaping study EC A

Behavioral: Vaping study EC B

Behavioral: Vaping study EC G

Behavioral: Vaping study EC C

Behavioral: Vaping study EC J

Older adult smokers

Active Comparator group

Description:

Adult smokers

Treatment:

Behavioral: Vaping study EC F

Behavioral: Vaping study EC I

Behavioral: Vaping study EC H

Behavioral: Vaping study EC E

Behavioral: Vaping study EC D

Behavioral: Vaping study EC A

Behavioral: Vaping study EC B

Behavioral: Vaping study EC G

Behavioral: Vaping study EC C

Behavioral: Vaping study EC J