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Developing Methods for Completing Future Satiety Studies

U

University of Guelph

Status

Completed

Conditions

Lack of Satiety

Treatments

Other: Yogurt

Study type

Interventional

Funder types

Other

Identifiers

NCT01379911
11AP036

Details and patient eligibility

About

Satiety is defined as the inhibition of eating, as a consequence of fullness after consuming food. Being able to effectively measure satiety is an important concept that has implications in the treatment and prevention of overweight and obesity. Increasing post-meal satiety is recognized a useful strategy for weight management. Recently, the category of foods marketed as having satiating effects has seen significant growth and this trend is expected to continue. The purpose of this project is to develop and validate methods for assessing the degree of satiety induced by foods and natural health products using commercially available food products.

This trial will examine the effects of a commercially available yogurt (containing added protein and fibre) on self-reported satiety and hunger, as well as food intake in both controlled and uncontrolled settings.

Enrollment

20 patients

Sex

Female

Ages

20 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Healthy women with regular hormonal contraceptive use, aged between 20 and 35 years
  • BMI of 20.0-24.9 kg/m2
  • Regular yogurt consumers (i.e. > 3 servings per week)

Exclusion criteria

  • Taking any regular medications or herbal supplements other than a multivitamin or folic acid supplement.
  • History of cardiovascular disease (including hypertension), diabetes, hypoglycemia, gum disease or any other medical condition
  • Vegans or vegetarians who exclude dairy products
  • Milk allergies or any other food allergies
  • Anyone with known anaphylactic allergic reactions, food or otherwise
  • Dislike or unwillingness to consume study foods
  • Gastrointestinal disease or disorders, including Celiac disease, lactose intolerance, irritable bowel syndrome, etc.
  • BMI <20.0 or > 25.0 kg/m2
  • Current participation in diet/weight-loss programs and/or changes of > 5 kg body weight within the past 6 months
  • Unusual dietary patterns (i.e. routinely skipping breakfast or other meals)
  • Unusual sleep patterns (i.e. shift workers)
  • High habitual intake of caffeinated beverages or alcohol
  • Restrained or disinhibited eaters, defined by the Three Factor Eating Questionnaire
  • Smokers

Trial design

Primary purpose

Basic Science

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Double Blind

20 participants in 2 patient groups, including a placebo group

Yogurt with added inulin
Active Comparator group
Description:
Yogurt with 6g of added inulin
Treatment:
Other: Yogurt
Regular yogurt
Placebo Comparator group
Description:
Regular yogurt without added inulin
Treatment:
Other: Yogurt

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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