Development and Testing of Adolescent Twelve-Step Facilitation

Mass General Brigham

Status

Completed

Conditions

Drug Dependence

Drug Abuse

Alcohol Abuse

Alcohol Dependence

Treatments

Behavioral: Cognitive Behavioral Therapy

Behavioral: Integrated Twelve-Step Facilitation

Study type

Interventional

Funder types

Other

Identifiers

NCT01449981

NIAAA R01AA019664

Details and patient eligibility

About

This study is the first to develop and test in a randomized experimental design the efficacy of an integrated 12-step facilitation intervention tailored for young people. In the first phase of the study, the investigators are developing and revising a preliminary manual for the two sessions individually-delivered Motivational Enhancement Therapy (MET) component and subsequent 8 session group-delivered Cognitive-Behavioral Therapy (CBT) component which will integrate Twelve-step Facilitation (TSF). Forty adolescents each will complete the preliminary integrated TSF protocol. In the second phase of the study, the investigators will compare integrated TSF (iTSF) to standard treatment (MET/CBT) in a randomized experimental design for adolescent substance use disorder with 60 adolescents. As a result, the investigators will examine potential mechanisms that may underlie the efficacy of iTSF in improving alcohol and other drug use outcomes. The investigators will test group differences on potential mechanisms of change (e.g., Alcoholics Anonymous/Narcotics Anonymous attendance and involvement) and whether these variables are associated with substance use outcomes.

Enrollment

59 patients

Sex

All

Ages

14 to 21 years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

Young people between the ages of 14 and 21 that meet criteria for alcohol or other drug abuse or dependence.

Exclusion Criteria: Youth

with an active psychotic disorders
who are in another substance use disorder (SUD) treatment program or receiving SUD related psychotherapy that could conflict with our treatment
with a history of severe or complicated withdrawal (e.g., alcohol seizure history)
who may be using alcohol/drugs prior to study entry at levels likely to result in severe withdrawal complications, in the absence of any history
taking addiction treatment medications (e.g., Buprenorphine)
who cannot speak English because the treatment and assessment instruments will be conducted in English