Development and Validation of a Digital Twin-based Clinical Research System (X Town Stage I)

Shanghai Jiao Tong University

Status: Enrolling

Conditions: Chronic Disease

Study type: Observational

Funder types: Other

Identifiers

NCT06861283

2025-KY-025(K)

Details and patient eligibility

About

Chronic diseases, characterized by their prolonged duration and slow progression, have emerged as predominant contributors to global morbidity and mortality. The investigators have developed a digital twin-based clinical research system (termed X Town) for chronic diseases, to predict clinical outcomes under various interventions. In this study, the investigators aim to evaluate the reliability of the developed digital twin-based clinical research system in predicting short-term clinical outcomes via virtual and real-world clinical studies.

Enrollment: 1,500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age≥18 years old
2. Receiving care at a community health service centre
3. Able to understand and comply with the study procedures
4. Agrees to participate in the study and signs the informed consent form

Exclusion criteria

1. Patients with severe mental illness
2. Patients expected to be unable to complete follow-ups

Trial design

1,500 participants in 2 patient groups

Virtual clinical studies

Real-world clinical studies