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Development and Validation of a Prediction Model for Depression and Anxiety in Perioperative Elderly Adults

C

Chinese PLA General Hospital (301 Hospital)

Status

Completed

Conditions

Predictive Model

Treatments

Other: no intervention

Study type

Observational

Funder types

Other

Identifiers

NCT05600504
PLAGH-DA-001

Details and patient eligibility

About

Anxiety and depression in later life are highly prevalent, often appear as comorbid disorders, and have many adverse consequences for both the individual and society. Given the disease burden, the large influx of new cases, and the economic costs, efforts should be made to prevent the onset of anxiety and depression in later life. Preventive interventions are likely to become more cost effective when they are targeted at elderly who have been exposed to risk factors known to be predictive of the onset of anxiety and/or depression. As the population aging is speeding up, senile diseases have become a significant and severe public health problem, influencing national health. More than 20 million elderly patients undergo surgery each year in China, accounting for a quarter of the population who undergo surgery. Therefore, it is necessary to construct a predictive model of anxiety and depression in perioperative elderly hospitalized patients

Full description

More than 20 million elderly patients undergo surgery each year in China, accounting for a quarter of the population who undergo surgery. Therefore, it is necessary to construct a predictive model of anxiety and depression in perioperative elderly hospitalized patients. In 2015, the WHO introduced the concept of "healthy ageing" for global ageing, with a focus on the mental health of older people at its core.

Previous studies have found a 31 percent risk of anxiety and 29 percent risk of depression in older perioperative patients. Therefore, optimizing perioperative mental health management in older patients remains one of the challenges facing clinicians.

Enrollment

6,386 patients

Sex

All

Ages

65+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. elective non-cardiac surgery,
  2. American society of Aneshesiologists (ASA) classification Ⅰ ~ Ⅲ,
  3. patients over age 65.

Exclusion criteria

  1. patient refused follow-up study,
  2. missing data exceeding 20%,
  3. went to ICU or died after surgery,
  4. have a history of any mental disorders such as epilepsy, Parkinson's disease, depression, anxiety, sleep disorders, or are currently taking relevant intervention drugs 5) patients with severe deafness, dementia or speech impairment.

Trial design

6,386 participants in 2 patient groups

No depression
Description:
no intervention
Treatment:
Other: no intervention
Depression
Description:
no intervention
Treatment:
Other: no intervention

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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