Development and Validation of a Preoperative Frailty Index Using Health Administrative Data

Ottawa Hospital Research Institute

Status: Completed

Conditions: Predictive Value of Tests; Surgery; Outcomes; Frail Elderly Syndrome

Treatments: Diagnostic Test: Frailty index

Study type: Observational

Funder types: Other

Identifiers

NCT03354546

DM8

Details and patient eligibility

About

The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard recommendations for creation of frailty indices.

Full description

The investigators will create a frailty index using health administrative data available for older people having surgery. The index will be based on the Canadian Study of Health and Aging Frailty Index and standard recommendations for creation of frailty indices.

Once derived the index will be tested to measure its association with outcomes, as well as its discrimination. Various representations of the frailty index will be tested (primary-as a continuous measure; secondary as a binary, categorical and fractional polynomial variable). Performance in subgroups will also be evaluated,

Enrollment: 511,285 patients

Sex: All

Ages: 66+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Having elective or emergency noncardiac surgery

Exclusion criteria

• no provincial health insurance number

Trial design

511,285 participants in 2 patient groups

Elective noncardiac surgery

Description:

Individuals having major noncardiac surgery following an elective hospital admission

Treatment:

Diagnostic Test: Frailty index

Emergency general surgery

Description:

Individuals having general surgery following an urgent hospital admission

Treatment:

Diagnostic Test: Frailty index