Development and Validation of a Prognostic Score for Early Death in Head Injury Patients. (SCORE TC)

University Hospital Center (CHU) Dijon Bourgogne

Status: Unknown

Conditions: Traumatic Brain Injury

Treatments: Other: death

Study type: Observational

Funder types: Other

Identifiers

NCT02861547

MIREK 2015

Details and patient eligibility

About

Traumatic brain injury (TBI) is a serious condition with high morbidity and mortality. The Glasgow score alone, assessed at the initial phase, is not enough to determine the prognosis.

The aim of this study is to define and to evaluate a prognostic score for early death based on clinical and CT-scan findings in an observational retrospective derivation cohort of patients hospitalized for traumatic brain injury.

This cohort will allow us to carry out a uni- and then multi-variate analysis so as to create a prognostic score for early death.

We will subsequently test this score in a prospective validation cohort.

Enrollment: 355 estimated patients

Sex: All

Ages: 15+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Traumatic brain injury (PMSI code (Programme Médicalisation des Systèmes d'Information) S 06.70 and S 06.71) Age>14 years Surviving more than 6h after the trauma Hospitalized in the traumatic brain injury intensive care unit and managed in accordance with international guidelines Who underwent a cerebral CT-scan

Exclusion criteria

Ongoing treatment with anticoagulants or antiplatelets Pregnant women Persons without national health insurance cover Children less than 15 years old Under guardianship.

Trial design

355 participants in 1 patient group

Traumatic brain injury

Treatment:

Other: death