Development of a Clinical and Biological Database in Peritoneal Carcinosis (BCB CARCINOSE)

Institut du Cancer de Montpellier - Val d'Aurelle

Status: Enrolling

Conditions: Peritoneal Carcinosis; Cancer

Treatments: Other: Tissues collections; Biological: biological collection

Study type: Interventional

Funder types: Other

Identifiers

NCT04221464

PROICM 2019-01 BCA

Details and patient eligibility

About

The creation of a prospective clinical-biological base dedicated to peritoneal carcinosis must therefore be able to serve as a support for this essential search for transfer.

Full description

The main objective is to improve the knowledge of carcinosis mechanisms to develop a specific treatment.

That's why this blood collection and tissue collection is very important for the future, these collection will be permitted to the scientists to develop a research specially for carcinosis.

Enrollment: 600 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient over the age of 18;
• Patient managed for peritoneal carcinosis : digestives origins (pancreatic, gastroesophageal junction, colorectal, bowel) or peritoneum cancer
• Patient eligible for a peritoneal carcinosis treatment : at least one (or more) surgery (s) ;chemotherapy or any treatment for this disease
• Patient agree will all study procedure : biological samples & tissues samples
• Patient giving informed consent

Exclusion criteria

• Patient not affiliated to Social Protection system
• Patient unable to understand or comply with study instructions or requirements for psychological, family, social or geographical reasons
• The level of French is insufficient to consent to the study and to response to the questionnaires
• Patient under guardianship
• Pregnancy ou breast-feeding women
• Patient treated in case of an emergency

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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600 participants in 1 patient group

Tumors and blood collection

Experimental group

Description:

For all the patients include in the study : * Blood samples will be collected at different times : before any treatment, at every surgery, one month after any surgery, at progression. * Tumours and not tumours tissues will be collected at different times : Before any surgery, one month after any surgery In parallel to this biological collection, standardized clinical data will be entered into a database treatment, at every surgery

Treatment:

Biological: biological collection

Other: Tissues collections