Development of a New Prognostic Assessment Tool for Postoperative Myocardial Injury (TROPUTILE)

Regional University Hospital Center (CHRU)

Status: Enrolling

Conditions: Perioperative Complication; Myocardial Injury

Study type: Observational

Funder types: Other

Identifiers

NCT04286685

29BRC19.0202 (TROPUTILE)

Details and patient eligibility

About

Myocardial injury after noncardiac surgery (MINS) is common, silent, and strongly associated with morbi-mortality.

There are some evidences in the littérature showing that troponin elevation pre and/or postoperatively and surgical Apgar score are strongly and independently associated with postoperative morbi-mortality.

In this cohort study of orthopedic surgery patients (> 50years), the aim is to determine MINS incidence and to assess wich peri-operative factors are associated with the occurrence of MINS. The final objective is to create a score to better identified the patients with a MINS and a poor outcome.

Enrollment: 1,600 estimated patients

Sex: All

Ages: 50 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• > 50 years
• orthopedic surgery (hip, knee, spine)
• written consent

Exclusion criteria

• no troponin measurement prior surgery
• sepsis
• acute coronary syndrome
• pulmonary embolism
• refusing to participate
• guardianship