Development of a Predictive Index for Probable Depression Among Secondary School Students

The Chinese University of Hong Kong

Status: Unknown

Conditions: Youth; Depression; Stress

Treatments: Other: Observation

Study type: Observational

Funder types: Other

Identifiers

NCT04063202

HMRF16171001

Details and patient eligibility

About

The present study aims to develop a new predictive index to predict future depression of adolescents by using factors including individual, interpersonal and environmental. The index can be used to predict likelihood of students who are non-probable depression cases convert into probable depression cases. In addition, the investigators also test the factors of depression remission. It can hence be used in school setting to identify high-risk students, and provide them with secondary interventions that are designed by considering modifiable significant variables identified in this unique, large-scale, longitudinal study.

Full description

A 12-month longitudinal study will be conducted in secondary school settings.

The investigators will investigate incidence of probable depression (i.e., from non-depression, CESD<16, at baseline to probable depression, CESD≥16, at month 12) and remission of probable depression.

The investigators will investigate factors that can prospectively predict new cases/remission of probable depression, including both well-documented risk/protective factors and some under-examined but potentially important local factors (e.g. school/academic stress, psychological resilience). The relative importance of the risk/protective factors at different socio-ecological levels will be compared and their combined effect will be identified.

Based on the selected factors, the investigators will derive a new prediction index called the Adolescent Depression Prediction Index (ADPI) in a model building sample and test its performance in predicting incidence of depression in a validation sample among secondary school students in Hong Kong.

Enrollment: 4,799 estimated patients

Sex: All

Ages: 12 to 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Secondary 1 (seventh year of formal education) to Secondary 4 Chinese students, who are studying local mainstream schools in Hong Kong.
• Able to read Chinese and speak either Cantonese or Mandarin.

Exclusion criteria

• Eligible students whose parents refuse to give consent to take part in the study.

Trial design

4,799 participants in 1 patient group

Non-cases

Description:

Secondary school students (seventh to tenth years of education) without probable depression at baseline interview.

Treatment:

Other: Observation