Development of a Radiomics Model With MR to Predict the Occurence of a Infiltration of Muscoskeletal Tumor

Scientific Institute for Research Hospitalization and Healthcare (IRCCS)

Status: Enrolling

Conditions: Bone Cancer Tumor; Soft Tissue Sarcoma (STS)

Study type: Observational

Funder types: Other

Identifiers

NCT06774729

MIT3

Details and patient eligibility

About

The goal of this observational study is to evaluate the feasibility and clinical utility of radiomics to diagnose peri-lesion tumour infiltration of tumours in participants with a suspect of Bone Cancer Tumor or Soft Tissue Sarcoma (STS).

The main questions it aims to answer are:

• is radiomics able to identify the ratio of participants truly diagnosed as positive to all those who had positive test results?
• is radiomics able to identify the likelihood that a participant who has a negative test result indeed does not have the disease?

Participants eligible for this study will get a MRI as part of their regular medical care. The only difference is that their data will be recorded and anonymously analyzed.

Enrollment: 122 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age over 18
• suspect of soft tissue sarcoma with a indication for surgical treatment
• suspect of bone cancer tumor with a indication for surgical treatment
• To give informed consent

Exclusion criteria

• simultaneous cancer or history of cancer in the last 5 years

• acute or chronic serious conditions that could

• contraindication to conduct a Contrast-enhanced magnetic resonance imaging (MRI) such as:

  • renal failure without dialysis
  • history of allergy to a paramagnetic contrast agent
  • claustrophobia
  • symptomatic epilepsy or history of epilepsy
  • cardiac pacemaker
  • infusion pump, prosthesis or any implant not compatible with MRI
  • pregnancy