Development of a Screening Tool for Difficult Embryo Transfers

ART Fertility Clinics LLC

Status: Completed

Conditions: Infertility

Treatments: Procedure: Embryo Transfer; Procedure: Oocyte Pick Up

Study type: Observational

Funder types: Other

Identifiers

NCT05701072

2208-ABU-007-BA

Details and patient eligibility

About

This study aims to investigate the accuracy of a proposed screening tool in identifying difficult embryo transfers (ETs) without doing a mock ET.

Full description

So far there has never been a screening tool to identify difficult ETs without doing a mock ET. This is a prospective, longitudinal study including at least 200 ETs. All women undergo a speculum examination at the time of transvaginal oocyte pick-up (OPU), the screening questionnaire will be filled by the Physician doing the OPU procedure. On the day of real ET, the Physician doing the ET will be blinded for the screening result, and fill a second questionnaire after the ET. Combined with the Embryologist recorded parameters, this second questionnaire will be used to categorize ETs as difficult or normal. Participants will NOT undergo any procedures beyond their routine treatment. Once the targeted number of participants are recruited, the questionnaires will be matched to see the accuracy of the screening questionnaire to identify difficult ETs.

Identification of difficult ETs with a non-invasive, free of cost questionnaire can enable selective mock transfers and facilitate the real ET for patients, who would otherwise be only recognized on the day of real ET, after their embryos have been already thawed for transfer.

Enrollment: 200 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• All women undergoing an ET is eligible.

Exclusion criteria

• No exclusion criteria, women can participate with multiple ET procedures.

Trial design

200 participants in 1 patient group

All participants

Treatment:

Procedure: Oocyte Pick Up

Procedure: Embryo Transfer