Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness

Mass General Brigham

Status: Enrolling

Conditions: Psychotic Disorders; Psychosocial Functioning; Anxiety Disorders; Depressive Disorder

Treatments: Behavioral: Resilience Training for Teens

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT05962879

2023P000985

K23MH131793 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This research study aims to develop a brief group-based treatment called Resilience Training for Teens, then to test how well it protects high school students with mild symptoms of depression, anxiety, or having unusual feelings from developing mental illnesses.

Enrollment: 70 estimated patients

Sex: All

Ages: 14 to 19 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Currently enrolled in 9th through 12th grade and between the ages of 14 and 19
• Endorsed at least one psychotic experience
• Provided contact information
• Have a parent or legal guardian who is able and willing to provide written informed consent (if under the age of 18)
• Have a parent or legal guardian who is able and willing to participate in a parent session
• Competent and willing to provide written informed assent (if under the age of 18) or consent (if age 18 or older)
• Able to communicate in English

Exclusion criteria

• Currently prescribed psychotropic medication (not including medications for attention deficit/hyperactivity disorder), regardless of adherence
• Currently obtaining psychotherapeutic intervention

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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70 participants in 2 patient groups

Resilience Training for Teens

Experimental group

Description:

A brief 6-session group-based behavioral intervention for teens at risk of a mental illness.

Treatment:

Behavioral: Resilience Training for Teens

Waitlist

No Intervention group

Description:

A one year waitlist period where participants will not participate in Resilience Training for Teens. Following that one year waitlist period, they can participate in Resilience Training for Teens.