Development of Bone Grafts Using Adipose Derived Stem Cells and Different Scaffolds

University of Zurich (UZH)

Status: Completed

Conditions: Overweight

Treatments: Procedure: Cell Culture

Study type: Observational

Funder types: Other

Identifiers

NCT01218945

Bone-ZH09

Details and patient eligibility

About

The repair of large osseous defects remains still unsolved. Aim of this study is to isolate and cultivate fat-derived progenitor cells and differentiation into osteoblasts. Therefore, our research idea is to pre-engineer large synthetic bone grafts and study the vascularization process in vivo.

Enrollment: 33 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• German-speaking patients aged 18-70 admitted to the Clinic of Reconstructive surgery for reconstructive surgery and fat-excision.

Exclusion criteria

• Drug-abuse, neoplasia and metabolic disorders

Trial design

33 participants in 1 patient group

Fat Removal

Description:

Patients undergoing surgical fat removal

Treatment:

Procedure: Cell Culture