Development of the Effectiveness of Rehabilitation Tools for Neurovisual Disorders in Patients With Posterior Cortical Atrophy (REEDUC-ACP)

Centre Hospitalier Universitaire de Nice

Status: Completed

Conditions: Posterior Cortical Atrophy

Treatments: Behavioral: Location of objects; Behavioral: Recognition of objects; Behavioral: Manipulation of objects

Study type: Interventional

Funder types: Other

Identifiers

NCT04041089

18-AOI-02

Details and patient eligibility

About

Posterior cortical atrophy (PCA) is manifested by neuro-visual disorders that alter the spatial location of objects, their manipulation and/or recognition. Its etiology is most often neurodegenerative, with a major impact on the autonomy and mood of patients and their families. Few studies have focused on non-medication management of these disorders.

The present study thus has a double objective: the development of a complete tool to work on the recognition, localization and/or manipulation of objects; and the evaluation of the effectiveness of this type of management.

Enrollment: 3 patients

Sex: All

Ages: 50+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age >50 years old
• Male or Female
• Patients with a diagnosis of PCA according to the criteria of Tang-Wai et al (2004)
• MMS>15
• Voluntary, written and informed consent of the patient himself or its legal representative (guardian/curator), with oral consent of the patient in all cases
• Anti-Alzheimer's and psychotropic treatments stable for one month, if taken by the patient
• Affiliation to a social security system

Exclusion criteria

• Uncorrected visual disorders with non-degenerative etiology (AV<0.5)
• Person under the protection of justice
• Pregnant women (a pregnancy test will be performed in premenopausal women)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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3 participants in 3 patient groups

Recognition of objects

Experimental group

Description:

Patients will do the therapy in the following order: object location, object manipulation and object recognition

Treatment:

Behavioral: Recognition of objects

Location of objects

Experimental group

Description:

Patients will do the therapy in the following order: object recognition, object location, and object manipulation

Treatment:

Behavioral: Location of objects

Manipulation of objects

Experimental group

Description:

Patients will do the therapy in the following order: object manipulation, object recognition and object location

Treatment:

Behavioral: Manipulation of objects