Development of the Partial Pressure of Carbon Dioxide During Exercise and at Night in Patients With Chronic Obstructive Pulmonary Disease (COPD) IV

Schön Klinik Berchtesgadener Land

Status: Completed

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Procedure: 6-minute walking test

Study type: Interventional

Funder types: Other

Identifiers

NCT01696916

Sentec2012

Details and patient eligibility

About

The aim of this study is to investigate the development of partial pressure of carbon dioxide during the 6-min walking test and during night in Chronic Obstructive Pulmonary Disease (COPD)-patients (GOLD stage IV). Therefore the partial pressure of carbon dioxide, oxygen saturation and the heart rate are registered by a device called "Sentec" during the mentioned periods. In addition a measurement of activity is realised by an activity monitor ("Sensewear").

Enrollment: 75 patients

Sex: All

Ages: 30 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• COPD IV with and without a respiratory insufficiency
• maximal paCO² of 55mmHg at admission (taken at rest by blood gas analysis without LTOT)

Exclusion criteria

• paCO² > 55mmHg
• non-invasive ventilation
• acute exacerbation

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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75 participants in 1 patient group

exercise testing

Experimental group

Description:

6-minute walking test with pCO2 and pO2 measurement

Treatment:

Procedure: 6-minute walking test