Development of Tools for Respiration and Circulation Exploration (MAPO-RCVQ)

Grenoble Alpes University Hospital Center (CHU)

Status: Completed

Conditions: Motor Activity

Treatments: Device: a set of wearable respiration and cardiac monitoring devices

Study type: Interventional

Funder types: Other

Identifiers

NCT02114749

University Hospital, Grenoble

Details and patient eligibility

About

This study is aimed to develop analysis methods and measurements tools for physiological variables : respiration, circulation and their mutual interactions and with the functions involved in the daily life in healthy volunteers (drinking, eating, sleeping, coughing...). The devices that are used are non invasive. The development of these tools needs to be validated on physiological signals obtained in healthy volunteers.

Full description

The analysis and interpretation of a record consist, for example, to measure the amplitude of the respiratory modulation of the cardiac period, a witness of the level of the subject's sympathetic activity.

To do this, a mathematical model of this oscillation is adjusted on the experimental data, and its characteristics (amplitude, phase, non-linearity...) are considered indexes of the interaction to be compared with the same characteristics in other conditions.

The transition to clinical applications requires validation of the developed tools on physiological signals recorded on healthy volunteers in a non-clinical environment, avoiding extra psychological stress in the Protocol followed.

Whether it is for the development of tools or their validation, it is essential that the sensors used are non-invasive.

Recorded situations are those of everyday life, such as working (only sedentary work are envisaged), eat, talk, rest and move from one place of life to another one.

Enrollment: 25 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy, major and socially insured human subjects

Exclusion criteria

• deprived of liberty, hospitalized and protected human subjects

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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25 participants in 1 patient group

volunteers in daily life activities

Experimental group

Description:

a set of wearable respiration and cardiac monitoring devices

Treatment:

Device: a set of wearable respiration and cardiac monitoring devices