Dexamethasone and Etoricoxib for Pain Prevention Following Periodontal Surgery

Universidade Estadual de Ponta Grossa

Status and phase: Completed; Phase 3; Phase 2

Conditions: Pain Control

Treatments: Procedure: Open Flap Debridement

Study type: Interventional

Funder types: Other

Identifiers

NCT00970112

08169/08

51/2008

Details and patient eligibility

About

The purpose of this study is to investigate whether preemptive medication with dexamethasone or etoricoxib provides better pain management and control than placebo following periodontal surgery.

Enrollment: 20 patients

Sex: All

Ages: 20 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients presenting moderate or severe periodontitis after nonsurgical periodontal treatment with clinical signs of inflammation

Exclusion criteria

• Pregnant
• Diabetes mellitus
• Heart diseases
• Allergic to components of the medications
• Risk of endocarditis

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Quadruple Blind

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20 participants in 3 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

Placebo 1 hour before surgery

Treatment:

Procedure: Open Flap Debridement

Etoricoxib

Experimental group

Description:

Etoricoxib 1 hour before surgery

Treatment:

Procedure: Open Flap Debridement

Dexamethaone

Experimental group

Description:

Dexamethasone 1 hour before surgery

Treatment:

Procedure: Open Flap Debridement