Dexamethasone for ESPB in Pain Management After Pediatric Idiopathic Scoliosis Surgery

Poznan University of Medical Sciences (PUMS)

Status and phase: Completed; Phase 4

Conditions: Scoliosis; Adolescence; Scoliosis; Scoliosis Idiopathic

Treatments: Drug: Dexamethasone; Drug: 0.9%NaCl

Study type: Interventional

Funder types: Other

Identifiers

NCT06616220

11/2024

Details and patient eligibility

About

Effect of perineurial dexamethasone on erector spinal plane block duration for pediatric, idiopathic scoliosis surgery.

Full description

This study proposes to explore the effect of perineurial Dexamethasone on erector spinal plane block duration for pediatric idiopathic scoliosis surgery.

Children need good analgesia after scoliosis surgery. Peripheral nerve blocks have provided a safe, effective method to control early postoperative pain when symptoms are most severe.

The safety of local anesthesia is essential in children due to the much lower toxicity threshold of local anesthetics. An effective adjuvant, such as Dexamethasone, could allow for a higher dilution of local anesthetics while maintaining and enhancing their analgesic effect.

Enrollment: 60 patients

Sex: All

Ages: 10 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• children scheduled for idiopathic scoliosis surgery
• age >10 and <18 years

Exclusion criteria

• age < 10 years
• age < 18 years
• infection at the site of the regional blockade
• coagulation disorders
• immunodeficiency
• ASA= or >4
• steroid medication in regular use

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups, including a placebo group

DEXAMETHASONE

Active Comparator group

Description:

0.2% ropivacaine + 0.1mg/kg Dexamethasone for erector spinae plane block

Treatment:

Drug: Dexamethasone

CONTROL

Placebo Comparator group

Description:

0.2% ropivacaine for erector spinae plane block

Treatment:

Drug: 0.9%NaCl