Dexamethasone for ESPB in Total Hip Arthroplasty

Poznan University of Medical Sciences (PUMS)

Status and phase: Completed; Phase 4

Conditions: Hip Arthropathy; Hip Osteoarthritis; Hip Arthritis

Treatments: Drug: Dexamethasone 4mg; Drug: 0.9%NaCl

Study type: Interventional

Funder types: Other

Identifiers

NCT06789042

10/2024

Details and patient eligibility

About

Effect of adding Dexamethasone to Erector Spinae Plane Block in Patients undergoing Total Hip Arthroplasty

Full description

Hip arthroplasty is one of the most common orthopaedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prostheses. Regional anaesthesia methods may be performed to reduce the inflammatory response, opioid consumption, and opioid-related side effects.

Enrollment: 60 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients scheduled for total hip arthroplasty
• patients aged >65 and <100 years
• patients able to provide informed consent
• patients able to reliably report symptoms to the research team

Exclusion criteria

• inability to provide first-party consent due to cognitive impairment or a language barrier

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups

Control group

Active Comparator group

Description:

Ultrasound-guided ESPB - 20ml 0,2% ropivacaine + 2ml 0.9% NaCl

Treatment:

Drug: 0.9%NaCl

Dexamethasone

Active Comparator group

Description:

Ultrasound-guided ESPB - 20ml 0,2% ropivacaine + 4mg Dexamethasone

Treatment:

Drug: Dexamethasone 4mg