Dexamethasone for Pain After Shoulder Surgery

University of Aarhus

Status and phase: Completed; Phase 4

Conditions: Arthritis; Shoulder Impingement Syndrome

Treatments: Drug: Dexamethasone

Study type: Interventional

Funder types: Other

Identifiers

NCT01414569

2011-003082-15 (EudraCT Number)

KTB-002

Details and patient eligibility

About

The purpose of this study is to determine if a dose of 40 mg dexamethasone is more effective as pain treatment than the currently used dose of 8 mg after arthroscopic shoulder surgery.

Enrollment: 97 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Arthroscopic subacromial decompression and/or acromioclavicular resection
• General anaesthesia
• Daysurgery, Horsens Hospital

Exclusion criteria

• Incompetent
• Pregnant
• Age under 18 or over 90 years
• Allergy toward dexamethasone
• Diabetes
• Active gastric ulcer
• Untreated hypertension
• Glaucoma
• Daily use of glucocorticoids or strong opioids
• Daily use of analgesics for unrelated illness
• Myasthenia gravis
• Mitochondrial disorders

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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97 participants in 3 patient groups, including a placebo group

8 mg dexamethasone

Active Comparator group

Treatment:

Drug: Dexamethasone

Placebo, saline

Placebo Comparator group

Treatment:

Drug: Dexamethasone

40 mg dexamethasone

Experimental group

Treatment:

Drug: Dexamethasone