Dexamethasone with Ropivacaine for PENG Block in Total Hip Arthroplasty

Poznan University of Medical Sciences (PUMS)

Status and phase: Enrolling; Phase 4

Conditions: Hip Osteoarthritis; Hip Arthritis; Hip Pain Chronic

Treatments: Drug: Ropivacaine+Dexamethasone; Drug: Ropivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT06470334

8/2024

Details and patient eligibility

About

Does adding Dexamethasone to the Periarticular Nerve Group Block in Patients undergoing Total Hip Arthroplasty reduce the dose of ropivacaine?

Full description

Hip arthroplasty is one of the most common orthopaedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prostheses. Regional anaesthesia methods may be performed to reduce the inflammatory response, opioid consumption, and opioid-related side effects.

Enrollment: 60 estimated patients

Sex: All

Ages: 65 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients scheduled for total hip arthroplasty
• patients aged >65 and <100 years
• patients able to provide informed consent
• patients able to reliably report symptoms to the research team

Exclusion criteria

• inability to provide first-party consent due to cognitive impairment or a language barrier

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups

Ropivacaine

Active Comparator group

Description:

Ultrasound-guided PENG block - 20ml 0,2% ropivacaine

Treatment:

Drug: Ropivacaine

Ropivacaine + Dexamethasone

Active Comparator group

Description:

Ultrasound-guided PENG block - 10ml 0,2% ropivacaine + 4mg Dexamethasone

Treatment:

Drug: Ropivacaine+Dexamethasone