Dexamethasone With TAP Block Increasing the Duration of the Peripheral Nerve Block in Caesarian Section
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About
Nowadays Cesarean sections became the most popular surgery worldwide with the consumption of the hospital resources and the continuous need to decrease the costs, work load and medical stuff engagement. One of the most common problem is the need to control pain post operatively, this issue increase the work load over the pain management team and increase lead to patient in satisfaction.
This study will test the usage of dexamethasone with different doses (4 and 8 mg) either locally or intravenously (I.V.) with the local anesthetics in TAP (transversus abdominis plane) block to prolong the duration of the block and decrease the need of post-operative analgesics.
Full description
Nowadays Cesarean sections became the most popular surgery worldwide with the consumption of the hospital resources and the continuous need to decrease the costs, work load and medical stuff engagement. One of the most common problem is the need to control pain post operatively, this issue increase the work load over the pain management team and increase lead to patient in satisfaction.(1,2,3) The presence of the adjuvant which can be added to the conventional anesthetic medications can prolong the duration of action and decrease the need for frequent post-operative analgesics.(4,5) The idea of adding a catheter or placing an epidural catheter still have a quite limitation regarding the patients compliance, delayed ambulation and high costs, these limitations redirect the anesthetist again to the use of adjuvant with a single shot block to prolong the duration of it and decrease the need of subsequent analgesics.(6) Dexamethasone proved to be an effective adjuvant in prolongation of the nerve blocks with the question regarding the proper route and dose (7,8,9,10).
This study will test the usage of dexamethasone with different doses (4 and 8 mg) either locally or intravenously (I.V.) with the local anesthetics in TAP (transversus abdominis plane) block to prolong the duration of the block and decrease the need of post-operative analgesics.
Enrollment
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Volunteers
Inclusion criteria
- Any patient ASA (american society of anesthesia) I or II,
- aged between 18 and 45 scheduled for elective cesarean section.
Exclusion criteria
- patient refusal,
- age below 18 or above 45 years,
- coagulopathy with INR (international normalized ratio) more than 1.5 or platelets below 100000,
- uncontrolled diabetes, uncontrolled hypertensive, addict patient,
- psychological instability, and
- allergy to the used drugs,
- failure of spinal,
- conversion to general of anesthesia,
- failure of application of TAP block.
Trial design
Primary purpose
Allocation
Interventional model
Masking
150 participants in 5 patient groups, including a placebo group
Trial contacts and locations
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Central trial contact
Hassan Ali
Data sourced from clinicaltrials.gov
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