Dexmedetomidine Adjuvant in Retinal Surgery

King Saud University

Status and phase: Unknown; Phase 3

Conditions: Peribulbar Anesthesia

Treatments: Drug: DEXMEDETOMIDINE

Study type: Interventional

Funder types: Other

Identifiers

NCT02282787

E-14-1291

Details and patient eligibility

About

During LA in retinal surgery there is some problem as regard the lack of anaesthesia duration and unexpected globe movement .so many adjuvant was added to LA to overcome this disadvantages of LA such as clonidine and fentanyl .

The investigators hypothesis is adding dexmedetomidine to pribulbal blocking LA will prolong anaesthesia duration and improve globe akinesia and decrease intraoperative supplementation of LA.There are Many studies had described the effects of dexmedetomidine on peripheral nerve blocks, spinal but up to date no knowledge is available on the impact of dexmedetomidine adjuvant to local anaesthetic in ophthalmic surgery

Enrollment: 90 estimated patients

Sex: All

Ages: 40 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients
• Going for elective vitreoretinal surgery.

Exclusion criteria

• History of coagulation abnormalities.
• Allergy to local anesthetics.
• Cardiac, hepatic or renal failure,
• Chronic clonidine or analgesic therapy.
• One-eyed patients

Trial design

90 participants in 2 patient groups

5 micron dex arm

Experimental group

Treatment:

Drug: DEXMEDETOMIDINE

10 micron dex arm

Experimental group

Treatment:

Drug: DEXMEDETOMIDINE