Dexmedetomidine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy Pain

Tanta University

Status: Completed

Conditions: External Oblique Intercostal Plane Block; Thoracotomy; Dexmedetomidine; Adjuvant; Pain

Treatments: Drug: Dexmedetomidine; Drug: Saline

Study type: Interventional

Funder types: Other

Identifiers

NCT06684535

36264PR904/10/24

Details and patient eligibility

About

This study aims to evaluate the role of dexmedetomidine as an adjuvant in external oblique intercostal plane block for post-thoracotomy pain.

Full description

External oblique intercostal plane block (EOIPB) is a novel block that has been described as an important modification of the fascial plane blocks that can consistently involve the upper lateral abdominal walls.

Dexmedetomidine is a selective alpha 2- adrenoceptor agonist possessing sedative, anxiolytic, and analgesic properties without the development of respiratory depression.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-III.
• Scheduled for open thoracotomy.

Exclusion criteria

• Patients with neurological or intellectual disability.
• Infection at the injection site.
• Drug abuse.
• Allergic reaction to local anesthetics.
• Coagulation abnormalities.
• Pregnancy.
• Body Mass Index (BMI) ≥35 kg/m2.
• Severe cardiovascular problems.
• Diabetic neuropathy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups

Dexmedetomidine group

Experimental group

Description:

Patients will receive 29 ml bupivacaine 0.25% + 1 ml dexmedetomidine 0.5 μg/kg.

Treatment:

Drug: Dexmedetomidine

Control group

Active Comparator group

Description:

Patients will receive 29 ml bupivacaine 0.25% + 1 ml saline.

Treatment:

Drug: Saline