Dexmedetomidine for Sedation Undergoing Bronchoscopy

Kaohsiung Medical University

Status: Unknown

Conditions: Safety Issues

Treatments: Procedure: bronchoscopy

Study type: Observational

Funder types: Other

Identifiers

NCT04169685

KMUHIRB-E(I)-20190221

Details and patient eligibility

About

Several sedatives or analgesics can be used to achieve appropriate levels of sedation for endoscopic procedures. Dexmedetomide is notable for providing sedation without respiratory depression. We hypothesized dexmedetomide is more suitable for sedation of bronchoscopy than other sedative drugs.

Full description

A retrospective chart review was conducted. All patients undergoing flexible bronchoscopy with moderate sedation were enrolled.The primary analysis outcome was safety profile during procedure included incidence of procedure interruption, incidence of snoring and observed apnea, transient hypoxemia and hypotension. The secondary outcome was measured by recovery profile (awake and ambulation time).

Enrollment: 80 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• sedation undergoing flexible bronchoscopy

Exclusion criteria

• without sedation undergoing flexible bronchoscopy

Trial design

80 participants in 2 patient groups

with dexmedetomidine

Description:

Drugs provided moderate sedation during procedure including dexmedetomidine

Treatment:

Procedure: bronchoscopy

without dexmedetomidine

Description:

Drugs provided moderate sedation during procedure without dexmedetomidine

Treatment:

Procedure: bronchoscopy