Dexmedetomidine in Sonographic Guided Erector Spinae Plane Block

Assiut University

Status and phase: Enrolling; Phase 3; Phase 2

Conditions: Pain Management

Treatments: Drug: Dexmedetomidine

Study type: Interventional

Funder types: Other

Identifiers

NCT06899841

04-2024-200943

Details and patient eligibility

About

to investigate the postoperative analgesic effect of dexmedetomidine addition with different doses as an adjuvant to bupivacaine to Erector spinae plane block after renal surgeries.

Enrollment: 90 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age between 18 and 70 years.
• Both sexes, males and females.
• Patients with the American Society of Anesthesiologists (ASA) physical status I/II.
• Body mass index (BMI) of 18-35 kg/m2
• Patients scheduled for elective Renal or Percutaneous Nephrolithotomy.

Exclusion criteria

• Patients under 18 years.
• Patient refusal of nerve block.
• Infection at the site of injection.
• Coagulopathy.
• Allergy to used medications.
• Psychiatric disorder or chronic pain syndromes.
• Chronic opioid use or substance abuse.
• Quadriplegic patients.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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90 participants in 3 patient groups

low dose dex

Experimental group

Description:

0.5 mic/kg of dexmedetomidine administered

Treatment:

Drug: Dexmedetomidine

intermediate dose dex

Experimental group

Description:

0.75 mic/kg of dexmedetomidine administered

Treatment:

Drug: Dexmedetomidine

high dose dex

Experimental group

Description:

1 mic/kg of dexmedetomidine administered

Treatment:

Drug: Dexmedetomidine