Dexmedetomidine on Pediatric Heart Operation

Gachon University Gil Medical Center

Status: Completed

Conditions: Acute Renal Injury

Treatments: Drug: Dexmedetomidine; Drug: no dexmedetomidine

Study type: Interventional

Funder types: Other

Identifiers

NCT01920542

GCIRB2013-163

Details and patient eligibility

About

we hypothized dexmedetomidine could reduce the reduction of renal function after cardiopulmonary bypass weaning in pediatric patients

Full description

dexmedetomidine, a2-adrenoreceptor agonist has been used for sedation or hemodynamic stability for operative procedure. It had been already reported that dexmedetomidine reduce the impairment of renal functon after cardiac operation in adult. we hypothized dexmedetomidine could reduce the reduction of renal function after cardiopulmonary bypass weaning in pediatric patients

Enrollment: 30 patients

Sex: All

Ages: 1 to 6 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1-6yr pediatric cardiac patients

Exclusion criteria

• previous renal dysfunction

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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30 participants in 2 patient groups

no dexmedetomidine

Experimental group

Description:

no administration of dexmedetomidine

Treatment:

Drug: no dexmedetomidine

dexmedetomidine

Active Comparator group

Description:

administration of 0.5ug/kg dexmedetomidine for 10 min and infusion of 0.5ug/kg/h of dexmedetomidine until weaning of cardiopulmonary bypass

Treatment:

Drug: Dexmedetomidine