Dexmedetomidine Sedation in Children With Respiratory Morbidities

Universitair Ziekenhuis Brussel

Status: Completed

Conditions: Respiratory Morbidity

Treatments: Drug: Dexmedetomidine

Study type: Observational

Funder types: Other

Identifiers

NCT02555605

DEXMRI20

Details and patient eligibility

About

This study aimed to determine the feasibility of dexmedetomidine in children with respiratory morbidities who required deep sedation for magnetic resonance imaging (MRI) scans.

Full description

Electronic medical records of children with at least 3 characteristics of respiratory morbidities were retrospectively reviewed. All study patients received dexmedetomidine bolus over 10 min followed by a continuous infusion to achieve a minimum Ramsay Sedation Score of 5. Patients were monitored for hemodynamics, total dose of dexmedetomidine received, adverse events experienced and sedation characteristics.

Enrollment: 19 patients

Sex: All

Ages: 1 month to 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Children up to the age of 16 years with at least 3 characteristics of respiratory morbidities

Exclusion criteria

• Children who had an American Society of Anaesthesiologists (ASA) physical status classification IV
• Documented pre-existing cardiac conduction abnormalities
• Renal impairment