Dexmedetomidine Versus Dexamethasone as Adjuvants to Bupivacaine in Caudal Epidural Block

Sohag University

Status: Enrolling

Conditions: İnguinal Hernia

Treatments: Drug: Dexamethasone; Drug: Dexmedetomidine

Study type: Interventional

Funder types: Other

Identifiers

NCT07056244

soh-Med-25-6-13MS

Details and patient eligibility

About

The goal of This prospective, randomized, double-blind comparative study is to compare the efficacy of dexamethasone and dexmedetomidine as adjuvants to bupivacaine 0.125% in caudal epidural block for pediatrics undergoing inguinal hernia surgery, aged 2-6 years.

of Both sex.

Enrollment: 80 estimated patients

Sex: All

Ages: 2 to 6 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Children aged 2-6 years.
• Both sexes.
• American Society of Anesthesiologists (ASA) physical status I and II.
• Scheduled for inguinal hernia surgery

Exclusion criteria

• Parents or legal guardians refusal.
• Known hypersensitivity to any study drugs.
• Abnormal sacral anatomy
• Local infection at the injection site.
• Neurological disease.
• Coagulopathy.
• Mental retardation.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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80 participants in 2 patient groups

group A will receive Bupivacaine + Dexmedetomidine

Active Comparator group

Description:

Patients will receive Bupivacaine 0.125% at 0.5 ml/kg + Dexmedetomidine 1.5 mcg/kg for post operative analgesia.

Treatment:

Drug: Dexmedetomidine

group B will receive Bupivacaine + Dexamethasone

Active Comparator group

Description:

Patients will receive Bupivacaine 0.125% at 0.5 ml/kg + Dexamethasone 0.2 mg/kg for post operative analgesia.

Treatment:

Drug: Dexamethasone