Dextroamphetamine as an Adjunct in Cocaine Treatment - 1

National Institutes of Health (NIH)

Status and phase: Completed; Phase 2

Conditions: Substance-Related Disorders; Cocaine-Related Disorders

Treatments: Drug: Dextroamphetamine; Drug: Placebo; Drug: D-Amphetamine

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT00000304

NIDA-09262-1

P50-09262-1

Details and patient eligibility

About

The purpose of this study is to evaluate dextroamphetamine sulfate (sustained release) as an adjunct in cocaine treatment; an evaluation of the ""replacement"" strategy.

Enrollment: 120 patients

Sex: All

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Please contact site for information.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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120 participants in 3 patient groups

1

Experimental group

Description:

15/30 mg d-amphetamine

Treatment:

Drug: Dextroamphetamine

2

Experimental group

Description:

30/60 mg d-amphetamine

Treatment:

Drug: D-Amphetamine

3

Experimental group

Description:

placebo

Treatment:

Drug: Placebo