Diabetes, Insulin Resistance and Body Composition

Xuan Song

Status: Completed

Conditions: Insulin Resistance, Diabetes

Treatments: Other: Diabetes，Insulin resistance，Control

Study type: Observational

Funder types: Other

Identifiers

NCT06724068

S1181

Details and patient eligibility

About

The goal of this retrospective study is to learn about the correlation between diabetes, insulin resistance and body compositions.

The main question[s] it aims to answer are:

• [The difference of body composition between the individuals of insulin resistance and diabetes]
• [The effect of diabetes on body composition]

Enrollment: 515 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Adults aged 18 years and older.
2. Diagnosed with type 2 diabetes mellitus according to recognized diagnostic criteria.
3. Availability of complete body composition data (e.g., DXA measurements).
4. Documented HbA1c levels and other glycemic control data.
5. Continuous medical records available during the study period

Exclusion criteria

1. Presence of other severe metabolic diseases, such as liver failure or kidney failure.
2. Use of medications affecting muscle mass (e.g., glucocorticoids) for more than three months.
3. History of malignancy or ongoing treatment for cancer.
4. Missing critical research data (e.g., diabetes duration or HbA1c levels).
5. History of surgeries causing significant body composition changes (e.g., bariatric surgery).

Trial design

515 participants in 3 patient groups

Diabetes

Treatment:

Other: Diabetes，Insulin resistance，Control

Insulin resistance

Treatment:

Other: Diabetes，Insulin resistance，Control

Control

Treatment:

Other: Diabetes，Insulin resistance，Control