Diabetic Retinopathy and OCT-A Changes Post-cataract Surgery

Uptown Eye Specialists

Status

Unknown

Conditions

Cataract

Macular Edema Due to Diabetes Mellitus

Diabetic Retinopathy

Treatments

Procedure: Cataract surgery

Study type

Observational

Funder types

Other

Identifiers

NCT04660006

OCTa Study 1.0

Details and patient eligibility

About

The purpose of this study is to use optical coherence tomography angiography (OCT-A) to compare retinal vasculature after uncomplicated cataract surgery in patients with and without diabetic retinopathy.

Full description

Patients undergoing cataract surgery who provided informed consent were enrolled in the study. There were three comparison groups: control, diabetic retinopathy (DR) and diabetic macular edema (DME) groups. Optical coherence tomography angiography (OCT-A) scans measuring retinal thickness, vessel density, perfusion density, and foveal avascular zone were obtained at baseline and postoperative week one, month one and month three.

Enrollment

170 estimated patients

Sex

All

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

All patients at Uptown Eye Specialists undergoing uneventful cataract surgery who have provided informed consent to the study.

Exclusion criteria

Other ocular co-morbidities such as axial length < 22.0 mm or > 25.0 mm, previous ocular surgeries, previous history of uveitis, previous ocular trauma, cornea pathologies or glaucoma, intraocular pressures over 22 mmHg
In groups 1 and 2: previous retinal laser treatments
OCT-A signal strength < 6
Use of multifocal intraocular lens
Second eye (if first eye recruited)
In Group 1: No diabetes mellitus as past medical history