Diagnosis and Comprehensive Treatment of Mediastinal Interventional Technique

Dan Liu

Status: Enrolling

Conditions: Mediastinal Diseases

Treatments: Procedure: Intraairway ultrasound-guided mediastinal opening technique

Study type: Observational

Funder types: Other

Identifiers

NCT06128681

Tianjinzyyhxkld

Details and patient eligibility

About

The goal of this observational study is to learn abou Whether patients undergoing mediastinal disease diagnosis and combined treatment with intrapacial ultrasound-guided mediastinal opening techniques have greater clinical benefit.

The participants were physically ill. The main questions it aims to answer are:

• Whether the mediastinal ultrasound-guided mediastinal opening technique is more beneficial for the diagnosis of benign or malignant mediastinal diseases.
• Does the mediastinal ultrasound-guided mediastinal opening technique benefit the patient by ablating mediastinal masses using freezing, laser, or other means.

Mediastinal diseases were diagnosed by lymph node biopsy combined with NGS, ROSE and other techniques using transairway ultrasound-guided mediastinal opening technique. Ablation of mediastinal malignancies is performed using techniques such as freezing or laser.

Researchers will compare the experimental group with mediastinal opening and the control group without mediastinal opening to see if Mediastinal open technique benefits patients.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Radiographic abnormalities of mediastinum
• Can tolerate general anesthesia
• Can tolerate bronchoscopy and has the condition to have mediastinal biopsy and treatment

Exclusion criteria

• Imaging or other tests can make a definitive diagnosis
• Cannot tolerate general anesthesia or tracheoscopic surgery
• Patients cannot sign informed consent forms

Trial design

30 participants in 2 patient groups

Mediastinal open group

Description:

Mediastinal opening technique was performed with intraairway ultrasound guidance

Treatment:

Procedure: Intraairway ultrasound-guided mediastinal opening technique

Non-mediastinal open group

Description:

Diagnosis and treatment are routinely performed without any manipulation of the mediastinum