Diagnosis of Active Tuberculosis by ELISPOT

National Taiwan University

Status: Unknown

Conditions: Tuberculosis

Study type: Observational

Funder types: Other

Identifiers

NCT00174083

9461700717

Details and patient eligibility

About

Recent studies revealed that the ex vivo enzyme-linked immunospot (ELISPOT) assay for gamma interferon is a specific method for contact tracing of Mycobacterium tuberculosis infection. However, its use in endemic area and bacillus Calmette-Guérin (BCG)-vaccinated hosts has not been proved. We hypothesize that the TB-ELISPOT assay can be a rapid and accurate diagnostic tool for active tuberculosis in clinical suspects in Taiwan.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients who present with fever or respiratory symptoms (cough, dyspnea, or hemoptysis) lasting for ≥ 2 weeks and have compatible radiographic findings were considered clinical suspects of TB.

Exclusion criteria