Diagnosis of Intracranial Hypertension Using TCCD, ONSD and ODH by Bedside Ultrasound

Central South University

Status: Not yet enrolling

Conditions: Traumatic Brain Injury

Treatments: Diagnostic Test: Invasive ICP; Diagnostic Test: ODH; Diagnostic Test: TCCD; Diagnostic Test: ONSD

Study type: Observational

Funder types: Other

Identifiers

NCT07151287

Ultrasound-ICP

Details and patient eligibility

About

The goal of this observational study is to investigate several means of measuring intracranial pressure (ICP) non-invasively in patients who had head trauma and received implantation of invasive ICP monitor device. The main questions it aims to answer are:

What are the diagnostic efficacies of Transcranial Color-Coded Doppler Ultrasound (TCCD), Optic Nerve Sheath Diameter (ONSD) and Optic Disc Height (ODH) (the 3 non-invasive way of measuring ICP) compared with invasive ICP monitor? Participants will receive simultaneous non-invasive measurements of TCCD, ONSD and ODH along with during the days of invasive ICP monitoring. The data will be compared among the techniques to study the diagnostic efficacy.

Enrollment: 64 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Traumatic brain injury;
• Received invasive ICP monitoring;
• age ≥ 18 years old.

Exclusion criteria

• Severe eyeball / eyelid damage prevents transorbital ultrasound examination;
• Allergy to ultrasound coupling agent;
• Pregnant or lactating females.

Trial design

64 participants in 1 patient group

Patients with traumatic brain injury and invasive ICP monitoring

Description:

Patients with traumatic brain injury and invasive ICP monitoring.

Treatment:

Diagnostic Test: ONSD

Diagnostic Test: TCCD

Diagnostic Test: ODH

Diagnostic Test: Invasive ICP