Diagnosis of PCL With EUS-FNA and Cross-sectional Imaging - A Report of Accuracy

Sahlgrenska University Hospital

Status: Unknown

Conditions: Pancreatic Cystadenocarcinoma; Pancreatic Cyst; Pancreatic Serous Cystadenoma; Solid Pseudopapillary Tumor of the Pancreas; Pancreatic Pseudocyst; Pancreatic Intraductal Papillary-Mucinous Neoplasm; Pancreatic Mucinous Cystadenoma; Pancreatic Neuroendocrine Carcinoma

Study type: Observational

Funder types: Other

Identifiers

NCT03884179

SahlgrenskaUHGEA2017

Details and patient eligibility

About

Pancreatic cystic lesions (PCLs) comprise of a heterogeneous group of entities that are benign, premalignant or malignant. With increased use of modern imaging techniques in recent years, incidentally discovered PCL have become much more common. However, imaging modalities for characterising PCL is a known clinical uncertainty since imaging is capable of detecting these lesions but may often not be able to distinguish malignant from benign lesions. Incorrect assessment of PCL can lead to fatal consequences because a malignant lesion may not be treated and a benign may be unnecessarily resected. The aim of this study was to assess the performance of endoscopic ultrasound with fine-needle aspiration (EUS-FNA) in the diagnosis of pancreatic cystic lesions compared to cross-sectional imaging modalities (CT/MRI). Our hypothesis is that EUS-FNA has a higher accuracy for diagnosing PCLs compared with cross-sectional imaging.

Enrollment: 58 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients with suspected PCLs according to radiology undergoing evaluation with EUS-FNA at a tertiarry endoscopy center from February 2007 until March 2017, who underwent pancreas resection

Oral and written consent of patients examined

Exclusion criteria

None