Diagnostic Accuracy of Nontuberculous Mycobacterial Lung Disease Based on Chest CT

Seoul National University

Status: Completed

Conditions: Mycobacterium Infections, Nontuberculous

Study type: Observational

Funder types: Other

Identifiers

NCT02340897

2014-1043

Details and patient eligibility

About

The aim of this study was to elucidate the accuracy and inter-rater agreement of diagnosis of nontuberculous mycobacterial lung disease based on chest computed tomography findings.

Full description

To elucidate the accuracy and inter-rater agreement of diagnosis of nontuberculous mycobacterial lung disease based on chest CT, two pulmonologists and two chest radiologists were requested to interpret chest CT of patients nontuberculous mycobacterial lung disease satisfying diagnostic criteria of American Thoracic Society as well as British Thoracic Society, or pulmonary tuberculosis. Two pulmonologists and two chest radiologists > 10 years of clinical experiences at a tertiary referral hospital participated as raters in this study. They were blinded to the any clinical information of the patients including the specific diagnosis, except age and sex. The interpretations of four raters were analyzed and compared.

Enrollment: 132 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Nontuberculous mycobacterial patients satisfying diagnostic criteria suggested by American Thoracic Society
• Patients with bacteriologically confirmed pulmonary tuberculosis
• Patients with bronchiectasis, confirmed by clinically as well as radiographically

Exclusion criteria

• None

Trial design

132 participants in 3 patient groups

Nontuberculous lung disease

Description:

Patients with Nontuberculous Mycobacteria satisfying American Thoracic Society and British Thoracic Society guidelines

pulmonary tuberculosis

Description:

Patients with culture confirmed tuberculosis

bronchiectasis

Description:

Patients with bronchiectasis based on chest CT findings as well as symptoms