Diagnostic and Imaging Indicators of Immunocardiomyopathic Patients

Chinese Academy of Medical Sciences & Peking Union Medical College

Status: Unknown

Conditions: Autoimmune Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT03885375

Immunocardiomyopathy

Details and patient eligibility

About

Cardiac involvements in autoimmune diseases (AD) is common but underestimated and an early detection remains a clinical challenge for lacking of efficient imaging methods. The objective of the study was to investigate LV myocardial abnormalities in AD patients by multimodal cardiac imaging, including speckle-tracking echocardiology (STE), cardiac magnetic resonance imaging (CMRI) and positron emission tomography (PET).

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient is diagnosed with autoimmune diseases, including systemic lupus erythematosus (SLE), vasculitis, dermatomyositis, sjogren's syndrome, scleroderma, rheumatoid arthritis and IgG4 associated disease.
• Patient is capable of complying with study procedures

Exclusion criteria

• Patient is pregnant or nursing
• Patient is complicated with congenital heart disease
• Patient had cardiac surgery before
• Patient is complicated with serious infections
• Patient is complicated with organ failure
• Patient is complicated with tumors
• Patient is diagnosed indefinitely
• Patient has been involved in other clinical trial