Diagnostic and Prognostic Value of Combination Biomarkers in the Critically Ill Patient With Sepsis.

Jianfeng Xie

Status: Unknown

Conditions: Diagnostic and Predictive Value

Study type: Observational

Funder types: Other

Identifiers

NCT01687010

PCT001

Details and patient eligibility

About

Sepsis is a common cause for morbidity and mortality in critically ill patients. With the development of medical skills, the mortality is still remain very high. Inappropriateness of initial antibiotic treatment is an important risk factor for mortality and effective antimicrobial administration within the first hour of documented hypotension was associated with increased survival to hospital discharge in adult patients with septic shock. However, the early treatment based on early diagnosis.But it is very difficult to diagnosis because of lack of specific clinic symptom and sign.When severe sepsis occur, biomarker could be helpful to diagnosis. Unfortunately, the diagnostic value of single biomarker is limited. Therefore, combine several biomarkers could enhance the diagnostic value.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Critically ill patients admitted into ICU

Exclusion criteria

• Age younger than 18 years
• Refuse to participate in this study