Diagnostic Criteria for Septic Arthritis

Zhejiang University

Status: Enrolling

Conditions: Septic Arthritis

Treatments: Diagnostic Test: History taking and physical examination; Diagnostic Test: biopsy; Diagnostic Test: Laboratory test

Study type: Observational

Funder types: Other

Identifiers

NCT05790434

2022-0909

Details and patient eligibility

About

Septic arthritis (SA) is a rare but highly disabling disease. The ideal diagnosis criteria is not well established. There is an urgent need to establish golden standard for diagnosis.

Full description

Septic arthritis (SA) is a rare but highly disabling disease. Epidemiologic studies have documented an incidence of 0.9-1.3 per 100,000 [1, 2]. The treatment is challenging and the ideal diagnosis criteria is not well established. The specific tactics employed by relevant researches varied widely [3-6]. Patients with recurrent sepsis may require arthrodesis or amputation, which would result in severe functional loss [2]. Therefore, there is an urgent need to establish golden standard for diagnosis.

Enrollment: 400 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• admission to orthopaedics
• complete data

Exclusion criteria

• Accompanied with fracture
• Accompanied with other infections
• Accompanied with immune system diseases

Trial design

400 participants in 2 patient groups

Cases

Description:

Patients with septic arthritis

Treatment:

Diagnostic Test: biopsy

Diagnostic Test: History taking and physical examination

Diagnostic Test: Laboratory test

Controls

Description:

Patients with osteoarthritis, rheumatoid arthritis

Treatment:

Diagnostic Test: biopsy

Diagnostic Test: History taking and physical examination

Diagnostic Test: Laboratory test