Diagnostic Efficacy of Metagenomic Next-generation Sequencing in Patients With Spinal Infections: A Retrospective Study

Sun Yat-sen University

Status: Enrolling

Conditions: Diagnositic Efficacy; Spinal Infection

Treatments: Other: No interventions

Study type: Observational

Funder types: Other

Identifiers

NCT06172153

SYSKY-2023-1095-01

Details and patient eligibility

About

Comparing the diagnostic efficacy between traditional laboratory methods and second-generation high-throughput sequencing in patients suspected of spinal infections.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

"Patients suspected of spinal infections, as per the American Infectious Diseases Society's 2015 criteria for primary vertebral osteomyelitis, were identified based on their clinical symptoms, laboratory tests, and imaging examinations. All cases included in the study underwent laboratory examinations, histopathological examinations, and second-generation high-throughput sequencing (metagenomic sequencing)."

Exclusion criteria

"The absence of laboratory examinations, histopathological examinations, and results from second-generation high-throughput sequencing (metagenomic sequencing)."

Trial design

100 participants in 1 patient group

Sun Yat-sen memorial hospital

Description:

Patients who were suspected of Spinal infection.

Treatment:

Other: No interventions