Diagnostic Pilot Study of Dual Energy Absorptiometry in the Detection of Osteopenia or Osteoporosis in Patients With Thalassemia Major

National Center for Research Resources (NCRR)

Status: Completed

Conditions: Osteopenia; Osteoporosis; Thalassemia Major

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00006138

199/15314

CHP-IRB-1998-6-1502

CHP-GCRC-1655

Details and patient eligibility

About

OBJECTIVES:

I. Determine the frequency and severity of osteopenia and osteoporosis in patients with thalassemia major who undergo dual energy x-ray absorptiometry, and correlate these findings with other relevant endocrinologic measurements.

Full description

PROTOCOL OUTLINE:

Patients undergo dual energy x-ray absorptiometry for bone density measurements, height (sitting and standing) and weight measurements, comprehensive endocrinologic examination, and assessment of the severity of iron overload at baseline, and then at years 1 and 2.

Sex: All

Ages: 6+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

• Diagnosis of thalassemia major with iron overload
• Not pregnant
• Negative pregnancy test