Diagnostic Utility of Exercise Cardiac Magnetic Resonance in the Assessment of Cardiac Dyspnea.

Mayo Clinic

Status: Completed

Conditions: Shortness of Breath; Cardiac; Dyspnea

Treatments: Diagnostic Test: Exercise cardiac magnetic resonance imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT03951779

18-005354

Details and patient eligibility

About

Researchers are examining the diagnostic utility of an exercise cardiac MRI (eCMR) in the assessment of cardiac dyspnea (shortness of breath).

Enrollment: 9 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Consecutive patients aged ≥18 years years with suspected cardiac dyspnea who are scheduled to undergo right heart catheterization as dictated by a comprehensive examination and echocardiography will be included for enrollment.

Exclusion criteria

• Age <18 years
• Pregnancy
• Mechanical ventilation
• Acute or chronic renal failure (creatinine clearance <30 ml/min or requiring renal replacement therapy)
• Inability to perform MRI (i.e. claustrophobia, severe obesity (>150 kg), device incompatible with MRI)
• Inability to exercise
• Significant arrhythmia that precludes adequate ECG-gating for the MRI (i.e. atrial fibrillation with highly variable cycle lengths)
• Prior heart or lung transplantation
• Left ventricular systolic (ejection fraction <50%) or diastolic failure (based on Framingham criteria for heart failure with preserved ejection fraction)
• Significant left-sided valvular disease (≥moderate aortic stenosis, mitral stenosis, aortic regurgitation, mitral regurgitation) or prior valve surgery

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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9 participants in 1 patient group

Subjects with unexplained but suspected cardiac dyspnea

Experimental group

Description:

Subjects with unexplained but suspected cardiac dyspnea who are being scheduled for right heart catheterization will undergo an exercise cardiac magnetic resonance imaging (eCMR).

Treatment:

Diagnostic Test: Exercise cardiac magnetic resonance imaging