Diagnostic Utility of Pleural Fluid MAGE Assay in Patients With Pleural Effusion From Primary Lung Cancer

Samsung Medical Center

Status: Completed

Conditions: Unilatral Pleural Effusion

Treatments: Procedure: pleural fluid tapping

Study type: Interventional

Funder types: Other

Identifiers

NCT01179685

2008-08-043

Details and patient eligibility

About

Melanoma antigen (MAGE) gene is known to be expressed in tumor cells, testis and placenta. The purpose of this prospective study was to investigate the sensitivity, specificity and accuracy of pleural fluid MAGE gene expression, tumor marker and cytology in the diagnosis of malignant pleural effusion.

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• unilateral pleural effusion on chest radiography

Exclusion criteria

• body temperature > 38.3ºC and peripheral blood leukocytosis (>12,000/μl)

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)