Diagnostic Value of Patient - Reported and Clinically Verified Olfactory Disorders (COVID-19) (COVID-OLFA)

University Hospital Center (CHU)

Status: Completed

Conditions: COVID-19

Treatments: Biological: Reporting of anosmia, ageusia and other clinical symptoms

Study type: Observational

Funder types: Other

Identifiers

NCT04407494

RECHMPL20_0176

Details and patient eligibility

About

Participants are healthcare workers and adult outpatients referred in a COVID-19 screening center. Patients-reported symptoms are collected, then participants underwent a simple olfactory test (CODA for Clinical Olfactory Dysfunction Assessment), prior to swabbing for SARS-CoV-2 diagnosis (RT-PCR). We aimed to evaluate the prevalence of smell and taste disorders, and to calculate the diagnostic value of patient-reported and clinically verified smell disorders in persons with suspected COVID-19.

Enrollment: 809 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Symptoms compatible with COVID-19
• Close exposure to a confirmed COVID-19 index case
• Ambulatory (asymptomatic, or if symptomatic, did not require hospitalisation, thus with initial mild disease)

Exclusion criteria

• known history of smell and taste disorders
• testing inability (cognitive impairment, non native French speakers, test malingering)
• testing contraindication (children, pregnancy, breastfeeding, specific allergies).

Trial design

809 participants in 1 patient group

COVID-19

Description:

Healthcare workers and adult outpatients attending the COVID-19 screening center of the University Hospital of Montpellier, France.

Treatment:

Biological: Reporting of anosmia, ageusia and other clinical symptoms